Glucose Role in Treatment of Alzheimers’ Disease
نویسنده
چکیده
1. Dong H, Csernansky JG (2009) Effects of Stress and Stress Hormones on Amyloidβ Protein and Plaque Deposition. J Alzheimers Dis 18: 459-469. 2. Csernansky JG, Dong H, Fagan AM, Wang L, Xiong C, et al. (2006) Plasma cortisol and progression of dementia in subjects with Alzheimer‐ type dementia. Am J Psychiatry 163: 2164-2169. 3. Swaab DF, Raadsheer FC, Endert E, Hofman MA, Kamphorst W, et al. (1994) Increased cortisol levels in aging and Alzheimer's disease in postmortem cerebrospinal fluid. J Neuroendocrinol 130: 1707-1712. 4. Strooper BD, Vassar R, Golde T (2010) The secretases: enzymes with therapeutic potential in Alzheimer disease. Nat Rev Neurol 6: 99-107. 5. Hardy J, Allsop D (1991) Amyloid deposition as the central event in the aetiology of Alzheimer's disease. Trends Pharmacol Sci 12: 383-388. 6. Hover S (1991) Abnormalities of glucose metabolism in Alzheimer's disease. Ann N Y Acad Sci 640: 53-58. 7. Chen Z, Zhong C (2013) Decoding Alzheimer's disease from perturbed cerebral glucose metabolism: implications for diagnostic and therapeutic strategies. Progress in Neurobiology 108: 21-43. Journal of Gerontology & Geriatric Research Gelbard, J Gerontol Geriatr Res 2016, 5:4 DOI: 10.4172/2167-7182.1000334
منابع مشابه
Alteration in the Expression of Alzheimer's-Related Genes in Rat Hippocampus by Exercise and Morphine Treatments
Introduction: Alzheimer's disease is a progressive brain disorder, which slowly eliminates memory and intellectual ability and eventually destroys the ability to carry out the simple tasks. β amyloid plaque and neurofibrillary tangles are two important signatures of this disease, which caused by mutant in Tau, BACE1, and APP genes. They could be important targets for treatment of Alzheimer's di...
متن کاملThe role of genetics in alzheimer’s disease
Alzheimer's disease is a progressive neurological disorder that causes the brain to shrink (atrophy) and brain cells die. Alzheimer's disease is the most common cause of dementia and causes a decrease in thinking skills and social behaviors. Alzheimer's disease is more common in people over 65 years old. The risk of developing Alzheimer's disease and other types of dementia increases with age,...
متن کاملDetection of Alzheimer\\\\\\\'s Disease using Multitracer Positron Emission Tomography Imaging
Alzheimer's disease is characterized by impaired glucose metabolism and demonstration of amyloid plaques. Individual positron emission tomography tracers may reveal specific signs of pathology that is not readily apparent on inspection of another one. Combination of multitracer positron emission tomography imaging yields promising results. In this paper, 57 Alzheimer's disease neuroimaging ini...
متن کاملRole of microRNA as a biomarker in Alzheimer’s disease
Introduction: MicroRNAs are small, non-coding, and protected RNA molecules that regulate gene expression after transcription by mRNA degradation or inhibition of protein synthesis. The function of these molecules is critical to many cellular processes, including growth, development, differentiation, homeostasis, apoptosis, aging, stress resistance. In addition, some diseases including cancer, a...
متن کاملP137: Stem Cell Therapy in Alzheimer’s Disease
Alzheimer disease (AD) is a progressive neurodegenerative brain disorder which plays an important role in neural cell destruction and as a result it causes memory loss in the patients. This disease is also the most common type of dementia which doesn’t completely respond to medical treatments so no certain cure is available. Recent studies show the advantages of using stem cells (SCs) in ...
متن کامل